Safety Genetics

Course Outline: (34 hours)

Contents:

1. Introduction, background, position and importance

2. Humoral safety: antibody structure and humoral safety response

3. Beta cells and immunoglobulin genes

4. Genetic basis of the diversity of antibodies

5. Cellular safety, cell-mediated immunity and genetic and environmental factors involved in cellular immunity

6. Complement system: polymorphism, association with diseases

7. Human leukocyte antigen (HLA) system of polymorphism and geographic extension and accompanying diseases

8. Blood groups: polymorphism, geographic extension and accompanying diseases

9. Organ transplants: genetics of autoimmune diseases

10. Discussion, conclusion and summary of the contents